منابع مشابه
Juvenile dermatomyositis.
Juvenile dermatomyositis (JDMS) is a chronic inflammatory condition characterized by muscle weakness and a distinctive rash caused by underlying vasculopathy. Long-term complications include subcutaneous and muscular calcification, contractures and in some cases the gradual development of a second connective tissue disease. Early aggressive treatment with systemic immunosuppressants and other a...
متن کاملJuvenile dermatomyositis.
The clinical profile of 7 children and their follow-up is described. There was female preponderance with mate to female ratio of 1:6. The median age of onset was 6 years. All the patients had skin rash, muscle weakness and abnormal enzyme profile. Muscle biopsy was performed in 6 and was abnormal in all of them. The electromyogram (EMG) was performed in 6 and was found abnormal in five. All the...
متن کاملJuvenile Dermatomyositis: A Review
Juvenile dermatomyositis is a systemic vasculopathy, affecting mainly the skin and muscle. In the United States, it is seen in more than three per million children per year. It is diagnosed on the basis of the criteria set by Bohan and Peter. The following review describes the characteristic clinical manifestations, the pathophysiology and immunology of the disease. The various treatment modali...
متن کاملJuvenile Dermatomyositis in Pregnancy
Juvenile dermatomyositis has variable clinical presentations both in and outside of pregnancy. A literature review indicated that optimal maternal and fetal outcomes can be anticipated when the pregnancy is undertaken while the disease is in remission. Poorer outcomes are associated with flare-up of the disease in early pregnancy compared with exacerbation in the second or third trimester, when...
متن کاملJuvenile dermatomyositis in Western Switzerland
Introduction Juvenile dermatomyositis (JDM) is a rare chronic, autoimmune vasculopathic disease with mainly muscle and skin involvement. The incidence described in USA is 2.5-4.1 cases per million children; the disease is slightly more common in girls. Recent studies describe that two third of the patients followed a chronic disease course, whereas only one third showed monocyclic disease course.
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ژورنال
عنوان ژورنال: Zeitschrift für Rheumatologie
سال: 2006
ISSN: 0340-1855,1435-1250
DOI: 10.1007/s00393-006-0109-5